Advicenne (ALDVI.PA)

10-Year Study

ALDVI.PA · Healthcare · Common Stock

About Advicenne (ALDVI.PA)

Healthcare

Advicenne S.A., a specialty pharmaceutical company, develops, commercializes, and safe treatments for rare renal diseases in France and internationally. It offers Sibnayal for the treatment of metabolic disorders....

Source: EODHD Financial Datasets
Fundamentals updated: Jul 31, 2026

Fundamental Snapshot

Advicenne (ALDVI.PA) reports a gross margin of -8.2% and an operating margin of -126.8%. Revenue changed +19.3% year-over-year while EPS changed +16.7%. Financially, its current ratio stands at 0.48x.

Executive Summary: Advicenne has compounded at -21.9% annually over the last 10 years, with a maximum drawdown of 93.6% and an annualized volatility of 94.0%.

1Y CAGRCAGRCompound Annual Growth Rate — the annualized rate of return over a period, accounting for compounding.Click for full definition →
-6.9%
3Y CAGRCAGRCompound Annual Growth Rate — the annualized rate of return over a period, accounting for compounding.Click for full definition →
-7.6%
5Y CAGRCAGRCompound Annual Growth Rate — the annualized rate of return over a period, accounting for compounding.Click for full definition →
-13.5%
10Y CAGRCAGRCompound Annual Growth Rate — the annualized rate of return over a period, accounting for compounding.Click for full definition →
-21.9%

History & Riski10-year historical performance analysis including CAGR, Max Drawdown, Sharpe & Sortino ratios, annual returns, and rolling volatility — all computed from daily market data.

10-Year Growth of $10,000

View full price history data
DateValue
2017-12-01$10,000
2018-01-01$9,454
2018-02-01$9,467
2018-03-01$9,444
2018-04-01$8,300
2018-05-01$8,649
2018-06-01$8,652
2018-07-01$8,409
2018-08-01$8,411
2018-09-01$8,989
2018-10-01$8,373
2018-11-01$8,280
2018-12-01$6,809
2019-01-01$7,672
2019-02-01$7,776
2019-03-01$7,455
2019-04-01$3,145
2019-05-01$2,941
2019-06-01$2,597
2019-07-01$2,882
2019-08-01$2,699
2019-09-01$2,875
2019-10-01$2,626
2019-11-01$2,202
2019-12-01$2,648
2020-01-01$2,750
2020-02-01$2,487
2020-03-01$1,799
2020-04-01$1,829
2020-05-01$1,617
2020-06-01$1,653
2020-07-01$1,653
2020-08-01$1,938
2020-09-01$2,216
2020-10-01$2,385
2020-11-01$2,282
2020-12-01$1,975
2021-01-01$2,312
2021-02-01$2,092
2021-03-01$2,246
2021-04-01$2,012
2021-05-01$2,268
2021-06-01$2,560
2021-07-01$2,787
2021-08-01$2,663
2021-09-01$2,421
2021-10-01$2,502
2021-11-01$2,275
2021-12-01$2,370
2022-01-01$2,297
2022-02-01$2,670
2022-03-01$2,363
2022-04-01$2,151
2022-05-01$2,085
2022-06-01$2,282
2022-07-01$2,129
2022-08-01$2,041
2022-09-01$1,960
2022-10-01$1,770
2022-11-01$1,719
2022-12-01$1,485
2023-01-01$1,741
2023-02-01$1,807
2023-03-01$1,975
2023-04-01$1,807
2023-05-01$1,697
2023-06-01$1,587
2023-07-01$1,821
2023-08-01$1,734
2023-09-01$1,500
2023-10-01$1,412
2023-11-01$1,105
2023-12-01$1,287
2024-01-01$1,156
2024-02-01$1,419
2024-03-01$1,529
2024-04-01$1,543
2024-05-01$1,529
2024-06-01$1,565
2024-07-01$1,302
2024-08-01$1,375
2024-09-01$1,280
2024-10-01$1,346
2024-11-01$1,178
2024-12-01$1,083
2025-01-01$1,214
2025-02-01$1,551
2025-03-01$1,251
2025-04-01$1,229
2025-05-01$1,251
2025-06-01$1,785
2025-07-01$1,756
2025-08-01$1,280
2025-09-01$1,273
2025-10-01$1,302
2025-11-01$1,315
2025-12-01$1,265
2026-01-01$1,225
2026-02-01$1,518
2026-03-01$1,053
2026-04-01$932
2026-05-01$640
2026-06-01$914
2026-07-01$1,200
Max DrawdownMax DrawdownThe largest peak-to-trough decline in the asset's value over the measurement period.Click for full definition →
93.6%
Sharpe RatioSharpe RatioRisk-adjusted return: how much excess return you earn per unit of total risk (volatility).Click for full definition →
-0.30
Sortino RatioSortino RatioLike Sharpe, but only penalizes downside volatility — a more accurate risk measure for asymmetric return distributions.Click for full definition →
-0.44
Ann. VolatilityAnnualized VolatilityThe annualized standard deviation of an asset's returns — a measure of how much prices fluctuate.Click for full definition →
50.2%
Best YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2021 · +20.0%
Worst YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2019 · -61.1%
% Positive Years% Positive YearsThe percentage of calendar years in the measurement period where the asset delivered a positive return.Click for full definition →
22%

Annual Returns

View full annual returns data
YearReturn
2018-31.9%
2019-61.1%
2020-25.4%
202120.0%
2022-37.3%
2023-13.3%
2024-15.9%
202516.9%
2026-5.2%

Rolling 12-Month Returns

Rolling 12-Month Annualised Volatility

Historical Drawdowns

Monthly Returns

Monthly Returns Heatmap

YearJanFebMarAprMayJunJulAugSepOctNovDecAnn.
2026-3.224.0-30.6-11.5-31.342.931.2-5.2%
202512.227.7-19.3-1.81.842.7-1.6-27.1-0.62.31.0-3.816.9%
2024-10.222.87.71.0-0.92.4-16.85.6-6.95.1-12.5-8.1-15.9%
202317.23.89.3-8.5-6.1-6.514.7-4.8-13.5-5.9-21.816.6-13.3%
2022-3.116.2-11.5-9.0-3.19.5-6.7-4.1-3.9-9.7-2.9-13.6-37.3%
202117.0-9.57.3-10.412.712.98.9-4.5-9.13.3-9.14.220.0%
20203.9-9.6-27.61.6-11.62.30.017.314.37.6-4.3-13.5-25.4%
201912.71.4-4.1-57.8-6.5-11.711.0-6.36.5-8.7-16.220.3-61.1%
2018-5.50.1-0.2-12.14.20.0-2.80.06.9-6.9-1.1-17.8-31.9%

Risk X-RayiA 19-factor macroeconomic risk decomposition showing exactly which market forces (equity beta, rates, inflation, credit, commodity, crypto) drive this asset's volatility. Powered by multivariate regression against daily factor returns.

Factor Risk Decomposition

Share of annualised volatility attributable to each macro factor.

Total Est. Vol
94.0%
View full factor risk breakdown
FactorRisk Exposure
VTI.US7.8%
VEA.US0.5%
VWO.US2.7%
QQQ.US0.0%
VTV.US0.5%
IJR.US0.2%
QUAL.US3.6%
SHV.US59.8%
TLT.US0.0%
LQD.US1.0%
HYG.US5.7%
GLD.US1.4%
USO.US0.1%
VNQ.US0.1%
BTC-USD.CC0.0%
CPER.US-0.2%
VIX.INDX0.1%
UUP.US1.5%
TIP.US0.0%
Idiosyncratic15.1%

Advicenne Business Fundamentals

Reported valuation multiples, trailing margins, YoY growth, and balance-sheet liquidity.

Valuation Multiples

Price-to-Sales (P/S)
4.12x
60th pct of 226 Healthcare peers · median 2.73x
Price-to-Book (P/B)
131.47x
98th pct of 229 Healthcare peers · median 3.44x

Profitability & Margins

Gross Margin (TTM)
-8.2%
12th pct of 183 Healthcare peers · median 57.1%
Operating Margin (TTM)
-126.8%
16th pct of 216 Healthcare peers · median 0.0%

Year-over-Year Growth

Revenue Growth (YoY)
+19.3%
72nd pct of 229 Healthcare peers · median +5.0%
EPS Growth (YoY)
+16.7%
54th pct of 201 Healthcare peers · median +14.1%

Financial Position

Current Ratio
0.48x
2nd pct of 220 Healthcare peers · median 2.70x

Dividend & Income Analysisi10-Year historical income simulation on a $10,000 initial investment, cumulative dividend income generated, average yield on cost, and annual payout table.

Income Simulation

Based on $10,000 initial investment.

Total Income Generated
$0
Avg Yield on Cost
0.00%

Momentum & MacroiPrice momentum indicators: distance from 50/200-Day SMA, 52-Week High proximity, Golden Cross trend signal, RSI momentum gauge, Fibonacci retracement levels, and Beta (market sensitivity).

vs 50-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+22.6%
Above/below 50-day moving average
vs 200-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+3.2%
Above/below 200-day moving average
vs 52-Week High52-Week HighThe highest price an asset reached in the past 52 weeks — a key reference for momentum and valuation context.Click for full definition →
35.4% from high
Distance from 52-week high
BetaBetaA measure of an asset's sensitivity to broad market movements relative to a benchmark (e.g. S&P 500).Click for full definition →
0.90
Market sensitivity coefficient
Trend SignalGolden Cross & Death CrossTechnical chart patterns that occur when a short-term moving average crosses over a long-term moving average.Click for full definition →
✦ Death Cross
Bearish — 50 SMA below 200 SMA
RSI (14-Day)Relative Strength Index (RSI)A momentum oscillator that measures the speed and change of price movements to identify overbought or oversold conditions.Click for full definition →
39
OversoldNeutralOverbought
Neutral
Fibonacci LevelsFibonacci RetracementTechnical levels based on mathematical ratios that indicate potential support and resistance areas.Click for full definition →
38.2% retracement-12.6%
50.0% retracement-1.9%
61.8% retracement+11.8%
% distance of current price from each 52-week Fibonacci support level.

In-Depth Analysis

ALDVI.PA — 10-Year Return & Risk Profile

Advicenne (ALDVI.PA) has delivered negative annualized growth of 21.9% over the last 10 years. A $10,000 investment at the start of the period would have grown to approximately $845, representing a total return of 92%. Over this period, ALDVI.PA generated positive annual returns in 2 out of 10 calendar years (22%).

The best single calendar year for ALDVI.PA was 2021, with a return of +20.0%. The worst year was 2019, when the asset declined 61.1%. This spread between best and worst year is a useful indicator of the range of outcomes an investor might have experienced in a given 12-month window.

The asset's Sharpe ratio of -0.30 is considered poor on a risk-adjusted basis. The Sharpe ratio measures return earned above the risk-free rate per unit of total volatility — a higher reading indicates more efficient return generation relative to the risk taken. Investors focused on risk-adjusted outcomes should weigh this figure alongside absolute CAGR when making allocation decisions.

ALDVI.PA — Drawdown, Volatility & Downside Risk

ALDVI.PA's annualized volatility of 50.2% is classified as high relative to the long-run US equity benchmark of approximately 15%. This above-average volatility means investors in ALDVI.PA have historically experienced larger day-to-day price swings than the broader market, which requires a higher tolerance for short-term portfolio fluctuations.

The asset's maximum peak-to-trough decline over the study period was 93.6% — a catastrophic peak-to-trough decline. Drawdown magnitude is a critical consideration for investors who may need to liquidate positions during market stress, as a larger decline requires proportionally greater subsequent gains to recover to the prior peak. A 94% drawdown, for example, requires a 1462% gain just to break even.

When evaluating ALDVI.PA for inclusion in a diversified US portfolio, it is important to note that historical volatility and drawdown metrics are backward-looking. They capture the risk environment of the past 10 years, which included the COVID-19 market crash (2020), the 2022 Federal Reserve rate hike cycle, and various geopolitical disruptions. Future risk may differ materially, particularly in response to structural changes in US monetary policy, sector regulation, or macroeconomic regime shifts.

ALDVI.PA — Macroeconomic Factor Risk Exposure

The macroeconomic factor model attributes 59.8% of ALDVI.PA's return variance to Short-Term Interest Rates. This means that when Short-Term Interest Rates rises or falls sharply, ALDVI.PA tends to move in the same direction with meaningful magnitude. Investors who already hold significant exposure to this factor — through other funds or direct equity positions — should be aware of this concentration when sizing their ALDVI.PA allocation.

The second-largest macro driver is US Equity (broad market), contributing 7.8% of variance. 15.1% of ALDVI.PA's risk is attributable to idiosyncratic, stock-specific factors that are uncorrelated with the broader macro drivers. A higher idiosyncratic share generally indicates that the fund's performance is more dependent on the security selection or holdings composition of the individual underlying assets, rather than broad market forces.

For US investors building a diversified multi-asset portfolio, understanding ALDVI.PA's factor exposures helps assess its marginal contribution to overall portfolio risk. Adding ALDVI.PA alongside assets with low correlation to Short-Term Interest Rates — such as US Treasury bonds, commodities, or assets with significant developed-market ex-US exposure — can reduce the overall portfolio's sensitivity to any single macroeconomic theme.

Compare this AssetiRun a head-to-head backtest and risk analysis against similar assets.

Frequently Asked Questions & Methodology

Is Advicenne a high-risk investment?

Advicenne (ALDVI.PA) has an annualized volatility of 94.0% and experienced a maximum drawdown of 93.6% over the last 10 years. Its primary macro risk driver is SHV.US.

What is the 10-year return of ALDVI.PA?

Over the past 10 years, ALDVI.PA has generated a Compound Annual Growth Rate (CAGR) of -21.9%. A $10,000 investment would have grown to approximately $845. It has had a positive return in 22% of calendar years.

What is ALDVI.PA's Sharpe ratio?

ALDVI.PA has a Sharpe ratio of -0.30 and a Sortino ratio of -0.44 over the 10-year period. The Sharpe ratio measures risk-adjusted return — how much excess return is earned per unit of volatility. A reading below 1.0 suggests investors were not fully compensated on a risk-adjusted basis.

What is ALDVI.PA's dividend yield?

ALDVI.PA does not pay a meaningful dividend. Its returns are driven primarily by price appreciation. Investors seeking regular income may wish to consider dividend-focused alternatives.

Is ALDVI.PA above its 200-day moving average?

ALDVI.PA is currently above its 200-day moving average by 3.2%. The current trend signal is: Bearish — 50 SMA below 200 SMA. The 200-day SMA is a widely used long-term trend filter — assets trading above it tend to exhibit positive price momentum.

Data Methodology & Trust

The risk and return information on this page is pre-calculated mathematically using daily market data spanning a 10-year period. Fundamentals (such as P/E Ratio, Market Cap, and Dividend Yield) represent trailing averages and may not immediately reflect real-time live market fluctuations. Advanced scoring models like the Piotroski F-Score and Altman Z-Score are proxies applied to publicly available trailing-twelve-month financial statements and may not account for recent off-balance-sheet events, qualitative company shifts, or sector-specific capital structures. Macroeconomic factor exposures are estimated via multivariate regression against standard market indices. This data is provided for quantitative insight and backtesting research, and should not be misconstrued as tailored financial advice.

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