Crescent Biopharma, Inc.

10-Year Study

CBIO.US · Healthcare · US · Common Stock

Executive Summary: Crescent Biopharma, Inc. has compounded at -30.9% annually over the last 10 years, with a maximum drawdown of 99.5% and an annualized volatility of 179.7%.

1Y CAGR
-8.0%
3Y CAGR
-53.9%
5Y CAGR
-39.7%
10Y CAGR
-30.9%

History & Riski10-year historical performance analysis including CAGR, Max Drawdown, Sharpe & Sortino ratios, annual returns, and rolling volatility — all computed from daily market data.

10-Year Growth of $10,000

Max DrawdownMax DrawdownThe largest peak-to-trough decline in the asset's value over the measurement period.Click for full definition →
99.5%
Sharpe RatioSharpe RatioRisk-adjusted return: how much excess return you earn per unit of total risk (volatility).Click for full definition →
0.19
Sortino RatioSortino RatioLike Sharpe, but only penalizes downside volatility — a more accurate risk measure for asymmetric return distributions.Click for full definition →
0.49
Ann. VolatilityAnnualized VolatilityThe annualized standard deviation of an asset's returns — a measure of how much prices fluctuate.Click for full definition →
124.9%
Best YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2017 · +175.2%
Worst YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2024 · -89.4%
% Positive Years% Positive YearsThe percentage of calendar years in the measurement period where the asset delivered a positive return.Click for full definition →
30%

Annual Returns

Rolling 12-Month Returns

Rolling 12-Month Annualised Volatility

Historical Drawdowns

Monthly Returns

Monthly Returns Heatmap

YearJanFebMarAprMayJunJulAugSepOctNovDecAnn.
2026-19.126.151.95.9————————64.0%
20258.00.0-22.219.0-16.0-23.1-23.015.9-17.47.218.0-21.2-52.6%
202427.1-3.73.8-40.0-85.03.7-21.4-18.2-5.6141.2-14.6-28.6-89.4%
20234.8-47.1-18.211.132.9-6.5-5.7-2.4-6.3-16.731.243.9-15.0%
2022-17.43.4-7.3-36.8-6.9-10.410.015.2-27.623.6217.640.3110.4%
2021-3.5-8.5-9.3-20.36.3-9.0-12.99.9-1.4-12.8-11.5-14.8-61.7%
2020-19.1-15.4-37.022.41.432.94.8-6.3-16.8-8.834.30.0-28.9%
201918.39.71.4-2.3-2.70.7-22.6-63.929.422.511.4-10.0-44.1%
201833.92.3-29.54.15.8-9.7-8.90.2-2.2-12.6-8.7-17.6-43.6%
2017-6.77.4-11.1-20.8195.1-12.12.36.814.7-17.822.719.0175.2%
2016———5.730.8-11.814.9-11.3-3.5-15.75.3-3.92.3%

Risk X-RayiA 19-factor macroeconomic risk decomposition showing exactly which market forces (equity beta, rates, inflation, credit, commodity, crypto) drive this asset's volatility. Powered by multivariate regression against daily factor returns.

Risk Profile Insight: This asset has an estimated annualized volatility of 179.7%. The dominant macroeconomic risk driver is SHV.US, accounting for 23.8% of variance. Idiosyncratic stock-specific factors contribute 28.7%.

10-Year Historical Price Series (Growth of $10,000)
DateSimulated Value
2016-03-0110000
2016-04-0110570.47044359185
2016-05-0113825.503589109432
2016-06-0112197.987931542888
2016-07-0114010.068579015775
2016-08-0112432.886664605654
2016-09-0111996.645637379233
2016-10-0110117.45028172363
2016-11-0110654.362456031877
2016-12-0110234.900563447258
2017-01-019546.979838131778
2017-02-0110251.677867704568
2017-03-019110.738810905357
2017-04-017214.766150992443
2017-05-0121291.947607806444
2017-06-0118724.83335721985
2017-07-0119161.07438444627
2017-08-0120469.799296510024
2017-09-0123473.15640470753
2017-10-0119295.303800811704
2017-11-0123674.498698871186
2017-12-0128171.142048269798
2018-01-0137734.90102104338
2018-02-0138607.38490588072
2018-03-0127231.545285634245
2018-04-0128338.927903534342
2018-05-0129983.22269574269
2018-06-0127063.759430369704
2018-07-0124647.65190040585
2018-08-0124697.987473946763
2018-09-0124161.075299638516
2018-10-0121107.38444828459
2018-11-0119278.524666169902
2018-12-0115889.262104286887
2019-01-0118791.948065402565
2019-02-0120620.806017132763
2019-03-0120906.04215412094
2019-04-0120419.46372296911
2019-05-0119865.772414019062
2019-06-0120000.00183038449
2019-07-0115486.577515959581
2019-08-015587.248663041408
2019-09-017231.543455249754
2019-10-018859.06094320079
2019-11-019865.77241401906
2019-12-018875.840077842591
2020-01-017181.2078817088395
2020-02-016073.825263808741
2020-03-013825.5035891094317
2020-04-014681.2083393049625
2020-05-014748.323047487678
2020-06-016308.725827255998
2020-07-016610.739268501481
2020-08-016191.2755455323695
2020-09-015151.007635814987
2020-10-014697.987473946765
2020-11-016308.725827255998
2020-12-016308.725827255998
2021-01-016090.604398450543
2021-02-015570.469528399605
2021-03-015050.336488733159
2021-04-014026.845883273086
2021-05-014278.523750977654
2021-06-013892.6182972921474
2021-07-013389.262561883011
2021-08-013724.832442027605
2021-09-013674.4968684866913
2021-10-013204.697571976667
2021-11-012835.5712529329626
2021-12-012416.107529963852
2022-01-011996.643806994741
2022-02-012063.758515177457
2022-03-011912.7517945547158
2022-04-011208.053764981926
2022-05-011124.1617525419006
2022-06-011006.7114708182716
2022-07-011107.3826179000987
2022-08-011275.1684731646415
2022-09-01922.8194583782463
2022-10-011140.9390567992102
2022-11-013624.1612949457776
2022-12-015083.892927632271
2023-01-015326.418872874855
2023-02-012818.79211829116
2023-03-012306.2844604200404
2023-04-012562.5382893556
2023-05-013404.5151558581547
2023-06-013184.8690167705317
2023-07-013001.830567530846
2023-08-012928.615187834972
2023-09-012745.5767385952863
2023-10-012287.9806154960716
2023-11-013001.830567530846
2023-12-014319.707402056583
2024-01-015491.153477190573
2024-02-015289.811183026918
2024-03-015491.153477190573
2024-04-013294.692086314343
2024-05-01494.20381294715145
2024-06-01512.50765787112
2024-07-01402.68458832730863
2024-08-01329.4692086314343
2024-09-01311.16536370746576
2024-10-01750.4576418827115
2024-11-01640.6345723389
2024-12-01457.59612309921437
2025-01-01494.20381294715145
2025-02-01494.20381294715145
2025-03-01384.3807434033401
2025-04-01457.59612309921437
2025-05-01384.3807434033401
2025-06-01295.4240570728528
2025-07-01227.33375395568967
2025-08-01263.57536690514746
2025-09-01217.63271614598636
2025-10-01233.37402278059932
2025-11-01275.47286610572706
2025-12-01217.08360079826727
2026-01-01175.53387282085862
2026-02-01221.29348513078003
2026-03-01336.2416312533027
2026-04-01356.0097837711888
Annual Return Matrix
YearAnnual Return
20171.7524587926999229
2018-0.4359738033672381
2019-0.44139381554742496
2020-0.2892249328596025
2021-0.6170213136343023
20221.1041666666666665
2023-0.1503150315031503
2024-0.8940677966101696
2025-0.5256000000000001
20260.6399662731871838
Total Factor Risk
1.7970338846270864
VTI.US Exposure
0.09434614910912295
VEA.US Exposure
0.08492227409496104
VWO.US Exposure
-0.00861819138341883
QQQ.US Exposure
-0.015836789043772184
VTV.US Exposure
0.030546797310805594
IJR.US Exposure
0.020897670213922304
QUAL.US Exposure
0.019605401584789753
SHV.US Exposure
0.23836800812749906
TLT.US Exposure
0.021635177454812585
LQD.US Exposure
0.1557992051585787
HYG.US Exposure
0.017116513944051233
GLD.US Exposure
0.007267387377349699
USO.US Exposure
-0.00121422913425274
VNQ.US Exposure
0.021056634625644808
BTC-USD.CC Exposure
-0.00003718277725473401
CPER.US Exposure
0.000051776700428151934
VIX.INDX Exposure
-0.006099416167271491
UUP.US Exposure
0.0000424960789432162
TIP.US Exposure
0.03275917274774835
Idiosyncratic Exposure
0.28739114397731247
Value Score
50
Growth Score
50
Profit Score
37.5
Health Score
23.6
Yield Score
0
Moat Score
40

Factor Risk Decomposition

Share of annualised volatility attributable to each macro factor.

Total Est. Vol
179.7%

FundamentalsiCompany financial health metrics: P/E valuation, dividend yield, Piotroski F-Score (9-point profitability signal), Altman Z-Score (bankruptcy risk proxy), and a radar chart across 6 fundamental dimensions. Note: ETFs may show N/A for some metrics.

Fundamental Dimensions

Core Valuation

P/E Ratio (TTM)P/E RatioPrice-to-Earnings ratio — the market price of a stock divided by its earnings per share, a key valuation measure.Click for full definition →N/A
Dividend YieldDividend YieldAnnual dividend paid per share divided by the current share price — expressed as a percentage income return.Click for full definition →0.00%
Market Cap$590.7M
Piotroski F-ScorePiotroski F-ScoreA 9-point scoring system evaluating a company's financial strength across profitability, leverage, and operating efficiency.Click for full definition →
9-point profitability signal
0.0/ 9
Weak
Altman Z-ScoreAltman Z-ScoreA bankruptcy prediction model that combines 5 financial ratios into a single score indicating financial distress risk.Click for full definition →
Bankruptcy risk proxy
1.18
Distress Zone
Income Simulation

Based on $10,000 initial investment.

Total Income Generated
$0
Avg Yield on Cost
0.00%

Momentum & MacroiPrice momentum indicators relative to key technical levels: distance from 50-Day SMA (intermediate trend), 200-Day SMA (long-term trend), 52-Week High (bullish proximity), and Beta (market sensitivity coefficient).

vs 50-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+48.2%
Above/below 50-day moving average
vs 200-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+51.1%
Above/below 200-day moving average
vs 52-Week High52-Week HighThe highest price an asset reached in the past 52 weeks — a key reference for momentum and valuation context.Click for full definition →
28.0% from high
Distance from 52-week high
BetaBetaA measure of an asset's sensitivity to broad market movements relative to a benchmark (e.g. S&P 500).Click for full definition →
1.00
Market sensitivity coefficient

Frequently Asked Questions & Methodology

Is Crescent Biopharma, Inc. a high-risk investment?

Crescent Biopharma, Inc. (CBIO.US) has an annualized volatility of 179.7% and experienced a maximum drawdown of 99.5% over the last 10 years. Its primary macro risk driver is SHV.US.

What is the 10-year return of CBIO.US?

Over the past 10 years, CBIO.US has generated a Compound Annual Growth Rate (CAGR) of -30.9%. It has had a positive return in 30% of the years measured.

Data Methodology & Trust

The risk and return information on this page is pre-calculated mathematically using daily market data spanning a 10-year period. Fundamentals (such as P/E Ratio, Market Cap, and Dividend Yield) represent trailing averages and may not immediately reflect real-time live market fluctuations. Advanced scoring models like the Piotroski F-Score and Altman Z-Score are proxies applied to publicly available trailing-twelve-month financial statements and may not account for recent off-balance-sheet events, qualitative company shifts, or sector-specific capital structures. Macroeconomic factor exposures are estimated via multivariate regression against standard market indices. This data is provided for quantitative insight and backtesting research, and should not be misconstrued as tailored financial advice.

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