Alto Neuroscience, Inc.

10-Year Study

ANRO.US · Healthcare · US · Common Stock

Executive Summary: Alto Neuroscience, Inc. has compounded at 27.5% annually over the last 10 years, with a maximum drawdown of 86.1% and an annualized volatility of 399.3%.

1Y CAGR
+1144.6%
3Y CAGR
+27.5%
5Y CAGR
+27.5%
10Y CAGR
+27.5%

History & Riski10-year historical performance analysis including CAGR, Max Drawdown, Sharpe & Sortino ratios, annual returns, and rolling volatility — all computed from daily market data.

10-Year Growth of $10,000

Max DrawdownMax DrawdownThe largest peak-to-trough decline in the asset's value over the measurement period.Click for full definition →
86.1%
Sharpe RatioSharpe RatioRisk-adjusted return: how much excess return you earn per unit of total risk (volatility).Click for full definition →
1.11
Sortino RatioSortino RatioLike Sharpe, but only penalizes downside volatility — a more accurate risk measure for asymmetric return distributions.Click for full definition →
3.21
Ann. VolatilityAnnualized VolatilityThe annualized standard deviation of an asset's returns — a measure of how much prices fluctuate.Click for full definition →
187.8%
Best YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2025 · +320.8%
Worst YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2026 · 46.4%
% Positive Years% Positive YearsThe percentage of calendar years in the measurement period where the asset delivered a positive return.Click for full definition →
100%

Annual Returns

Rolling 12-Month Returns

Rolling 12-Month Annualised Volatility

Historical Drawdowns

Monthly Returns

Monthly Returns Heatmap

YearJanFebMarAprMayJunJulAugSepOctNovDecAnn.
2026-13.027.214.215.9————————46.4%
20251.4-34.7-22.915.33.6-14.739.519.99.2253.0-2.428.5320.8%
2024——-0.31.0-22.9-10.60.818.8-10.7-66.013.4-4.1-72.5%

Risk X-RayiA 19-factor macroeconomic risk decomposition showing exactly which market forces (equity beta, rates, inflation, credit, commodity, crypto) drive this asset's volatility. Powered by multivariate regression against daily factor returns.

Risk Profile Insight: This asset has an estimated annualized volatility of 399.3%. The dominant macroeconomic risk driver is SHV.US, accounting for 43.6% of variance. Idiosyncratic stock-specific factors contribute 4.2%.

10-Year Historical Price Series (Growth of $10,000)
DateSimulated Value
2024-02-0110000
2024-03-019967.532467532466
2024-04-0110071.42857142857
2024-05-017766.233766233767
2024-06-016941.558441558441
2024-07-017000
2024-08-018318.181818181818
2024-09-017428.5714285714275
2024-10-012525.974025974026
2024-11-012863.636363636364
2024-12-012746.753246753247
2025-01-012785.714285714286
2025-02-011818.181818181818
2025-03-011402.5974025974028
2025-04-011616.8831168831168
2025-05-011675.3246753246754
2025-06-011428.5714285714287
2025-07-011993.5064935064934
2025-08-012389.6103896103896
2025-09-012610.38961038961
2025-10-019214.285714285714
2025-11-018993.506493506493
2025-12-0111558.441558441558
2026-01-0110051.948051948051
2026-02-0112785.714285714286
2026-03-0114597.402597402597
2026-04-0116922.077922077922
Annual Return Matrix
YearAnnual Return
20253.208037825059101
20260.46404494382022454
Total Factor Risk
3.992683433827168
VTI.US Exposure
0.060645390291904584
VEA.US Exposure
0.06880160404977469
VWO.US Exposure
0.003767288195567499
QQQ.US Exposure
-0.013049652237750394
VTV.US Exposure
0.0115122006999944
IJR.US Exposure
0.020205306261405116
QUAL.US Exposure
0.02360246596940761
SHV.US Exposure
0.4364637671036184
TLT.US Exposure
0.0009682111062869113
LQD.US Exposure
0.27792837721451297
HYG.US Exposure
0.035760005690581145
GLD.US Exposure
-0.00166769550036581
USO.US Exposure
0.0013894871389505932
VNQ.US Exposure
0.00042832604000598803
BTC-USD.CC Exposure
0.0004973971005341626
CPER.US Exposure
0.0034760982878436486
VIX.INDX Exposure
0.0011339442061540775
UUP.US Exposure
0.013845952357927129
TIP.US Exposure
0.012599565442178462
Idiosyncratic Exposure
0.041691960581468956
Value Score
50
Growth Score
50
Profit Score
37.5
Health Score
23.6
Yield Score
0
Moat Score
40

Factor Risk Decomposition

Share of annualised volatility attributable to each macro factor.

Total Est. Vol
399.3%

FundamentalsiCompany financial health metrics: P/E valuation, dividend yield, Piotroski F-Score (9-point profitability signal), Altman Z-Score (bankruptcy risk proxy), and a radar chart across 6 fundamental dimensions. Note: ETFs may show N/A for some metrics.

Fundamental Dimensions

Core Valuation

P/E Ratio (TTM)P/E RatioPrice-to-Earnings ratio — the market price of a stock divided by its earnings per share, a key valuation measure.Click for full definition →N/A
Dividend YieldDividend YieldAnnual dividend paid per share divided by the current share price — expressed as a percentage income return.Click for full definition →0.00%
Market Cap$692.6M
Piotroski F-ScorePiotroski F-ScoreA 9-point scoring system evaluating a company's financial strength across profitability, leverage, and operating efficiency.Click for full definition →
9-point profitability signal
0.0/ 9
Weak
Altman Z-ScoreAltman Z-ScoreA bankruptcy prediction model that combines 5 financial ratios into a single score indicating financial distress risk.Click for full definition →
Bankruptcy risk proxy
1.18
Distress Zone
Income Simulation

Based on $10,000 initial investment.

Total Income Generated
$0
Avg Yield on Cost
0.00%

Momentum & MacroiPrice momentum indicators relative to key technical levels: distance from 50-Day SMA (intermediate trend), 200-Day SMA (long-term trend), 52-Week High (bullish proximity), and Beta (market sensitivity coefficient).

vs 50-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+26.7%
Above/below 50-day moving average
vs 200-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+116.5%
Above/below 200-day moving average
vs 52-Week High52-Week HighThe highest price an asset reached in the past 52 weeks — a key reference for momentum and valuation context.Click for full definition →
0.0% from high
Distance from 52-week high
BetaBetaA measure of an asset's sensitivity to broad market movements relative to a benchmark (e.g. S&P 500).Click for full definition →
2.06
Market sensitivity coefficient

Frequently Asked Questions & Methodology

Is Alto Neuroscience, Inc. a high-risk investment?

Alto Neuroscience, Inc. (ANRO.US) has an annualized volatility of 399.3% and experienced a maximum drawdown of 86.1% over the last 10 years. Its primary macro risk driver is SHV.US.

What is the 10-year return of ANRO.US?

Over the past 10 years, ANRO.US has generated a Compound Annual Growth Rate (CAGR) of 27.5%. It has had a positive return in 100% of the years measured.

Data Methodology & Trust

The risk and return information on this page is pre-calculated mathematically using daily market data spanning a 10-year period. Fundamentals (such as P/E Ratio, Market Cap, and Dividend Yield) represent trailing averages and may not immediately reflect real-time live market fluctuations. Advanced scoring models like the Piotroski F-Score and Altman Z-Score are proxies applied to publicly available trailing-twelve-month financial statements and may not account for recent off-balance-sheet events, qualitative company shifts, or sector-specific capital structures. Macroeconomic factor exposures are estimated via multivariate regression against standard market indices. This data is provided for quantitative insight and backtesting research, and should not be misconstrued as tailored financial advice.

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