Akari Therapeutics PLC

10-Year Study

AKTX.US · Healthcare · US · Common Stock

Executive Summary: Akari Therapeutics PLC has compounded at -19.5% annually over the last 10 years, with a maximum drawdown of 99.7% and an annualized volatility of 390.3%.

1Y CAGR
+1764.2%
3Y CAGR
+45.9%
5Y CAGR
-14.4%
10Y CAGR
-19.5%

History & Riski10-year historical performance analysis including CAGR, Max Drawdown, Sharpe & Sortino ratios, annual returns, and rolling volatility — all computed from daily market data.

10-Year Growth of $10,000

Max DrawdownMax DrawdownThe largest peak-to-trough decline in the asset's value over the measurement period.Click for full definition →
99.7%
Sharpe RatioSharpe RatioRisk-adjusted return: how much excess return you earn per unit of total risk (volatility).Click for full definition →
1.31
Sortino RatioSortino RatioLike Sharpe, but only penalizes downside volatility — a more accurate risk measure for asymmetric return distributions.Click for full definition →
22.98
Ann. VolatilityAnnualized VolatilityThe annualized standard deviation of an asset's returns — a measure of how much prices fluctuate.Click for full definition →
785.8%
Best YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2026 · +5114.5%
Worst YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2025 · -76.3%
% Positive Years% Positive YearsThe percentage of calendar years in the measurement period where the asset delivered a positive return.Click for full definition →
29%

Annual Returns

Rolling 12-Month Returns

Rolling 12-Month Annualised Volatility

Historical Drawdowns

Monthly Returns

Monthly Returns Heatmap

YearJanFebMarAprMayJunJulAugSepOctNovDecAnn.
2026-18.70.42082.24.9204.3-8.3——————5114.5%
2025-10.7-20.242.516.1-6.3-13.3-12.0-26.232.9-25.7-35.2-40.5-76.3%
2024-16.0-10.3-20.6-17.411.357.543.3-1.0-23.0-18.6-49.60.8-60.9%
2023-0.6-26.1-47.2-0.5-2.2-4.047.1-37.025.4-13.7-13.55.8-66.8%
2022-8.7-1.5-11.1-0.8-1.7-14.514.04.4-47.1-26.018.7-15.0-68.7%
202136.832.4-21.2-22.0-12.9-3.6-6.413.6-11.41.8-1.8-8.0-18.9%
20202.92.2-21.232.46.26.9-7.8-14.41.2-13.86.715.65.7%
2019————-46.96.3-6.910.6-17.811.18.4-15.0-51.1%

Risk X-RayiA 19-factor macroeconomic risk decomposition showing exactly which market forces (equity beta, rates, inflation, credit, commodity, crypto) drive this asset's volatility. Powered by multivariate regression against daily factor returns.

Risk Profile Insight: This asset has an estimated annualized volatility of 390.3%. The dominant macroeconomic risk driver is SHV.US, accounting for 83.3% of variance. Idiosyncratic stock-specific factors contribute 8.8%.

10-Year Historical Price Series (Growth of $10,000)
DateSimulated Value
2019-04-0110000
2019-05-015307.262682936315
2019-06-015642.458433917561
2019-07-015251.396546846455
2019-08-015810.055776629225
2019-09-014776.536521198475
2019-10-015307.262682936315
2019-11-015754.190173318323
2019-12-014888.268260599238
2020-01-015027.933068044931
2020-02-015139.6648074456925
2020-03-014050.2794159250825
2020-04-015363.128819026176
2020-05-015698.324037228463
2020-06-016089.38539152061
2020-07-015614.525365872631
2020-08-014804.469589243406
2020-09-014860.3351925543075
2020-10-014189.944223370775
2020-11-014469.27383826216
2020-12-015167.597875490623
2021-01-017067.039043640458
2021-02-019357.542098861397
2021-03-017374.301726576773
2021-04-015754.190173318323
2021-05-015013.966800411944
2021-06-014832.402124509377
2021-07-014525.1399743520205
2021-08-015139.6648074456925
2021-09-014553.072509617992
2021-10-014636.871713752783
2021-11-014553.072509617992
2021-12-014189.944223370775
2022-01-013826.815670734079
2022-02-013770.949801033698
2022-03-013351.95537869662
2022-04-013324.0223106516896
2022-05-013268.1564409513085
2022-06-012793.29614891385
2022-07-013184.357503205997
2022-08-013324.0223106516896
2022-09-011759.7766270936215
2022-10-011301.6759627715373
2022-11-011544.6928289550447
2022-12-011312.8491367116137
2023-01-011304.4693228539263
2023-02-01963.6871846947523
2023-03-01508.3799137537421
2023-04-01505.58658697003807
2023-05-01494.41341302996193
2023-06-01474.8603586348285
2023-07-01698.3240372284625
2023-08-01439.9441567734054
2023-09-01551.6759960702225
2023-10-01476.25700537733803
2023-11-01412.01118862452984
2023-12-01435.75418324719186
2024-01-01365.9217795243456
2024-02-01328.2122841779034
2024-03-01260.4748672181639
2024-04-01215.08379813857687
2024-05-01239.3854780971906
2024-06-01377.09498676310676
2024-07-01540.5027888314612
2024-08-01534.9162018614231
2024-09-01412.01118862452984
2024-10-01335.195551189136
2024-11-01168.9944223370775
2024-12-01170.39106907958706
2025-01-01152.23464477762073
2025-02-01121.50838314372619
2025-03-01173.1843625646061
2025-04-01201.1173307134816
2025-05-01188.54749338155338
2025-06-01163.40781871769693
2025-07-01143.85474767322108
2025-08-01106.1452523267789
2025-09-01141.06145418820202
2025-10-01104.74860558426937
2025-11-0167.87709661839867
2025-12-0140.363129984480146
2026-01-0132.82122966649103
2026-02-0132.96089455718343
2026-03-01719.2737583453165
2026-04-01754.1899602067397
2026-05-012294.692786332728
2026-06-012104.748648206586
Annual Return Matrix
YearAnnual Return
20200.05714285714285716
2021-0.18918918918918914
2022-0.6866666793823242
2023-0.668085105087812
2024-0.6089743354616777
2025-0.7631147559404821
202651.145327902367185
Total Factor Risk
3.9032809098943235
VTI.US Exposure
0.02967243896887594
VEA.US Exposure
0.00008820719873395173
VWO.US Exposure
0.0010694553398922085
QQQ.US Exposure
-0.00031862963171234575
VTV.US Exposure
0.0006522574197101228
IJR.US Exposure
0.005798952208378916
QUAL.US Exposure
0.0027064329550273484
SHV.US Exposure
0.8328163962880718
TLT.US Exposure
0.00021837252773183392
LQD.US Exposure
0.006754926073049578
HYG.US Exposure
0.0003196547510802567
GLD.US Exposure
0.019299768607488967
USO.US Exposure
0.006190308427188508
VNQ.US Exposure
-0.00005596775601144909
BTC-USD.CC Exposure
0.0012647640162451975
CPER.US Exposure
-0.00004995308317188393
VIX.INDX Exposure
-0.00007789128696306766
UUP.US Exposure
0.0007236969688555475
TIP.US Exposure
0.005363097840664167
Idiosyncratic Exposure
0.08756371216686444
Value Score
43.5
Growth Score
50
Profit Score
37.5
Health Score
13.8
Yield Score
0
Moat Score
0

Factor Risk Decomposition

Share of annualised volatility attributable to each macro factor.

Total Est. Vol
390.3%

FundamentalsiCompany financial health metrics: P/E valuation, dividend yield, Piotroski F-Score (9-point profitability signal), Altman Z-Score (bankruptcy risk proxy), and a radar chart across 6 fundamental dimensions. Note: ETFs may show N/A for some metrics.

Fundamental Dimensions

Core Valuation

P/E Ratio (TTM)P/E RatioPrice-to-Earnings ratio — the market price of a stock divided by its earnings per share, a key valuation measure.Click for full definition →N/A
Forward P/EForward P/E RatioA valuation metric that compares the current stock price to estimated future earnings per share.Click for full definition →No estimate availableN/A
Dividend YieldDividend YieldAnnual dividend paid per share divided by the current share price — expressed as a percentage income return.Click for full definition →0.00%
Squeeze RiskShort Squeeze RiskA situation where a sharp rise in the price of a stock forces short sellers to buy shares to cover their positions, further driving up the price.Click for full definition →Extreme
Market Cap$18.8M
Piotroski F-ScorePiotroski F-ScoreA 9-point scoring system evaluating a company's financial strength across profitability, leverage, and operating efficiency.Click for full definition →
9-point profitability signal
1.0/ 9
Weak
Altman Z-ScoreAltman Z-ScoreA bankruptcy prediction model that combines 5 financial ratios into a single score indicating financial distress risk.Click for full definition →
Bankruptcy risk proxy
0.69
Distress Zone
Income Simulation

Based on $10,000 initial investment.

Total Income Generated
$0
Avg Yield on Cost
0.00%

Momentum & MacroiPrice momentum indicators: distance from 50/200-Day SMA, 52-Week High proximity, Golden Cross trend signal, RSI momentum gauge, Fibonacci retracement levels, and Beta (market sensitivity).

vs 50-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+110.0%
Above/below 50-day moving average
vs 200-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+593.8%
Above/below 200-day moving average
vs 52-Week High52-Week HighThe highest price an asset reached in the past 52 weeks — a key reference for momentum and valuation context.Click for full definition →
31.7% from high
Distance from 52-week high
BetaBetaA measure of an asset's sensitivity to broad market movements relative to a benchmark (e.g. S&P 500).Click for full definition →
0.65
Market sensitivity coefficient
Trend SignalGolden Cross & Death CrossTechnical chart patterns that occur when a short-term moving average crosses over a long-term moving average.Click for full definition →
✦ Golden Cross
Bullish — 50 SMA above 200 SMA
RSI (14-Day)Relative Strength Index (RSI)A momentum oscillator that measures the speed and change of price movements to identify overbought or oversold conditions.Click for full definition →
66
OversoldNeutralOverbought
Neutral
Fibonacci LevelsFibonacci RetracementTechnical levels based on mathematical ratios that indicate potential support and resistance areas.Click for full definition →
38.2% retracement+10.2%
50.0% retracement+35.9%
61.8% retracement+77.2%
% distance of current price from each 52-week Fibonacci support level.

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Frequently Asked Questions & Methodology

Is Akari Therapeutics PLC a high-risk investment?

Akari Therapeutics PLC (AKTX.US) has an annualized volatility of 390.3% and experienced a maximum drawdown of 99.7% over the last 10 years. Its primary macro risk driver is SHV.US.

What is the 10-year return of AKTX.US?

Over the past 10 years, AKTX.US has generated a Compound Annual Growth Rate (CAGR) of -19.5%. It has had a positive return in 29% of the years measured.

Data Methodology & Trust

The risk and return information on this page is pre-calculated mathematically using daily market data spanning a 10-year period. Fundamentals (such as P/E Ratio, Market Cap, and Dividend Yield) represent trailing averages and may not immediately reflect real-time live market fluctuations. Advanced scoring models like the Piotroski F-Score and Altman Z-Score are proxies applied to publicly available trailing-twelve-month financial statements and may not account for recent off-balance-sheet events, qualitative company shifts, or sector-specific capital structures. Macroeconomic factor exposures are estimated via multivariate regression against standard market indices. This data is provided for quantitative insight and backtesting research, and should not be misconstrued as tailored financial advice.

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