BioNTech SE

10-Year Study

22UA.XETRA · Healthcare · DE · Common Stock

Executive Summary: BioNTech SE has compounded at 5.8% annually over the last 10 years, with a maximum drawdown of 93.9% and an annualized volatility of 135.4%.

1Y CAGR
+1.2%
3Y CAGR
-4.8%
5Y CAGR
-12.7%
10Y CAGR
+5.8%

History & Riski10-year historical performance analysis including CAGR, Max Drawdown, Sharpe & Sortino ratios, annual returns, and rolling volatility — all computed from daily market data.

10-Year Growth of $10,000

Max DrawdownMax DrawdownThe largest peak-to-trough decline in the asset's value over the measurement period.Click for full definition →
93.9%
Sharpe RatioSharpe RatioRisk-adjusted return: how much excess return you earn per unit of total risk (volatility).Click for full definition →
0.96
Sortino RatioSortino RatioLike Sharpe, but only penalizes downside volatility — a more accurate risk measure for asymmetric return distributions.Click for full definition →
4.43
Ann. VolatilityAnnualized VolatilityThe annualized standard deviation of an asset's returns — a measure of how much prices fluctuate.Click for full definition →
263.4%
Best YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2026 · +257.0%
Worst YearBest & Worst YearThe single calendar year with the highest and lowest return in the measured period.Click for full definition →
2024 · -81.1%
% Positive Years% Positive YearsThe percentage of calendar years in the measurement period where the asset delivered a positive return.Click for full definition →
43%

Annual Returns

Rolling 12-Month Returns

Rolling 12-Month Annualised Volatility

Historical Drawdowns

Monthly Returns

Monthly Returns Heatmap

YearJanFebMarAprMayJunJulAugSepOctNovDecAnn.
2026305.3-3.6-18.712.4————————257.0%
2025560.2-9.8-22.810.6-7.58.24.8-10.0-3.57.3-0.2-73.233.2%
2024-7.1-5.53.2-2.810.3-18.45.9-0.633.6-2.410.0-84.2-81.1%
2023-7.3-7.8-7.0-10.2-3.60.6-0.214.9-12.0-11.76.90.7-33.6%
2022-29.7-10.713.2-10.112.6-6.412.9-8.2-6.01.413.7-10.6-32.4%
202129.5-2.51.669.56.113.640.85.0-15.10.224.5-28.4193.6%
2020—-15.5———-15.7-21.8-5.7-3.78.6142.0-25.7-1.3%
2019—————40.6-26.5-4.9-15.14.16.537.026.7%

Risk X-RayiA 19-factor macroeconomic risk decomposition showing exactly which market forces (equity beta, rates, inflation, credit, commodity, crypto) drive this asset's volatility. Powered by multivariate regression against daily factor returns.

Risk Profile Insight: This asset has an estimated annualized volatility of 135.4%. The dominant macroeconomic risk driver is SHV.US, accounting for 47.0% of variance. Idiosyncratic stock-specific factors contribute 28.5%.

10-Year Historical Price Series (Growth of $10,000)
DateSimulated Value
2019-05-0110000
2019-06-0114060.06166157014
2019-07-0110327.880608494983
2019-08-019822.947292210038
2019-09-018337.09561039571
2019-10-018679.05040837663
2019-11-019246.66038454354
2019-12-0112671.413596229879
2020-02-0110703.004937123698
2020-06-019024.224623402037
2020-07-017056.068246873798
2020-08-016653.360360897843
2020-09-016406.874984977268
2020-10-016955.39094430031
2020-11-0116831.768483787666
2020-12-0112508.993846887519
2021-01-0116197.590270447587
2021-02-0115787.921733071393
2021-03-0116034.753926685624
2021-04-0127184.52168911728
2021-05-0128838.55775784488
2021-06-0132772.25056493751
2021-07-0146141.68546931148
2021-08-0148455.624456789585
2021-09-0141119.570308605165
2021-10-0141205.28461043829
2021-11-0151283.7798228632
2021-12-0136731.668077440554
2022-01-0125839.00850430665
2022-02-0123070.84273465574
2022-03-0126121.82404091401
2022-04-0123473.637464108495
2022-05-0126430.34692483098
2022-06-0124743.97271428177
2022-07-0127937.86326456437
2022-08-0125637.91490634456
2022-09-0124093.043933653524
2022-10-0124422.84784917183
2022-11-0127772.961306805213
2022-12-0124822.08416795716
2023-01-0122999.483582198067
2023-02-0121194.241097255726
2023-03-0119718.8025278317
2023-04-0117713.9418834967
2023-05-0117080.37120368521
2023-06-0117184.519808585726
2023-07-0117142.86036662552
2023-08-0119701.44442701495
2023-09-0117337.271095773154
2023-10-0115313.316540539725
2023-11-0116375.632310525023
2023-12-0116493.667396078945
2024-01-0115316.788160703074
2024-02-0114476.65608117222
2024-03-0114945.324803224554
2024-04-0114520.051333214102
2024-05-0116012.848003454881
2024-06-0113061.970864606827
2024-07-0113834.406350952346
2024-08-0113747.61584686858
2024-09-0118364.870664124945
2024-10-0117930.918143706116
2024-11-0119718.8025278317
2024-12-013113.1752887824373
2025-01-0120551.99136703586
2025-02-0118538.451672292478
2025-03-0114311.754123413062
2025-04-0115830.587944878971
2025-05-0114650.237089339751
2025-06-0115847.946045695724
2025-07-0116603.023431224494
2025-08-0114945.324803224554
2025-09-0114424.581778721957
2025-10-0115483.425928543908
2025-11-0115457.388777318776
2025-12-014147.718269622271
2026-01-0116811.32064102553
2026-02-0116212.466162847546
2026-03-0113174.798519915725
2026-04-0114806.459996690528
Annual Return Matrix
YearAnnual Return
2020-0.012817808219177995
20211.9364206687638674
2022-0.3242320464285663
2023-0.3355244755244755
2024-0.8112502687229806
20250.33231118869777587
20262.569784405351847
Total Factor Risk
1.3535940320462163
VTI.US Exposure
0.004278800995683376
VEA.US Exposure
0.025209106813827462
VWO.US Exposure
-0.0011700135441418133
QQQ.US Exposure
0.016327225139192308
VTV.US Exposure
0.005073362047299031
IJR.US Exposure
0.010979847161139882
QUAL.US Exposure
0.022425587737131405
SHV.US Exposure
0.47046275744100857
TLT.US Exposure
-0.006726809658824117
LQD.US Exposure
0.07164359029424112
HYG.US Exposure
-0.0012992585983213677
GLD.US Exposure
0.015318920626071167
USO.US Exposure
0.0023208092859778946
VNQ.US Exposure
0.020037117533396088
BTC-USD.CC Exposure
0.0037547679716216005
CPER.US Exposure
-0.00009554670107972777
VIX.INDX Exposure
0.005370593013619505
UUP.US Exposure
0.04440987310842695
TIP.US Exposure
0.006546404286546079
Idiosyncratic Exposure
0.2851328650471845
Value Score
50
Growth Score
50
Profit Score
37.5
Health Score
23.6
Yield Score
0
Moat Score
40

Factor Risk Decomposition

Share of annualised volatility attributable to each macro factor.

Total Est. Vol
135.4%

FundamentalsiCompany financial health metrics: P/E valuation, dividend yield, Piotroski F-Score (9-point profitability signal), Altman Z-Score (bankruptcy risk proxy), and a radar chart across 6 fundamental dimensions. Note: ETFs may show N/A for some metrics.

Fundamental Dimensions

Core Valuation

P/E Ratio (TTM)P/E RatioPrice-to-Earnings ratio — the market price of a stock divided by its earnings per share, a key valuation measure.Click for full definition →N/A
Dividend YieldDividend YieldAnnual dividend paid per share divided by the current share price — expressed as a percentage income return.Click for full definition →0.00%
Market Cap$20.5B
Piotroski F-ScorePiotroski F-ScoreA 9-point scoring system evaluating a company's financial strength across profitability, leverage, and operating efficiency.Click for full definition →
9-point profitability signal
0.0/ 9
Weak
Altman Z-ScoreAltman Z-ScoreA bankruptcy prediction model that combines 5 financial ratios into a single score indicating financial distress risk.Click for full definition →
Bankruptcy risk proxy
1.18
Distress Zone
Income Simulation

Based on $10,000 initial investment.

Total Income Generated
$0
Avg Yield on Cost
0.00%

Momentum & MacroiPrice momentum indicators relative to key technical levels: distance from 50-Day SMA (intermediate trend), 200-Day SMA (long-term trend), 52-Week High (bullish proximity), and Beta (market sensitivity coefficient).

vs 50-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
+1.3%
Above/below 50-day moving average
vs 200-Day SMAMoving Averages (SMA)A rolling average of an asset's price over a defined window — used to identify trends and momentum signals.Click for full definition →
-2.8%
Above/below 200-day moving average
vs 52-Week High52-Week HighThe highest price an asset reached in the past 52 weeks — a key reference for momentum and valuation context.Click for full definition →
17.7% from high
Distance from 52-week high
BetaBetaA measure of an asset's sensitivity to broad market movements relative to a benchmark (e.g. S&P 500).Click for full definition →
1.59
Market sensitivity coefficient

Frequently Asked Questions & Methodology

Is BioNTech SE a high-risk investment?

BioNTech SE (22UA.XETRA) has an annualized volatility of 135.4% and experienced a maximum drawdown of 93.9% over the last 10 years. Its primary macro risk driver is SHV.US.

What is the 10-year return of 22UA.XETRA?

Over the past 10 years, 22UA.XETRA has generated a Compound Annual Growth Rate (CAGR) of 5.8%. It has had a positive return in 43% of the years measured.

Data Methodology & Trust

The risk and return information on this page is pre-calculated mathematically using daily market data spanning a 10-year period. Fundamentals (such as P/E Ratio, Market Cap, and Dividend Yield) represent trailing averages and may not immediately reflect real-time live market fluctuations. Advanced scoring models like the Piotroski F-Score and Altman Z-Score are proxies applied to publicly available trailing-twelve-month financial statements and may not account for recent off-balance-sheet events, qualitative company shifts, or sector-specific capital structures. Macroeconomic factor exposures are estimated via multivariate regression against standard market indices. This data is provided for quantitative insight and backtesting research, and should not be misconstrued as tailored financial advice.

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